Tabriz University of Medical Sciences Medical Journal of Tabriz University of Medical Sciences 2783-2031 39 1 2017 04 05 The effect of hydro ethanol extract of parsley leaves (petroselinum crispum) on spermatogenesis in male wistar rats receiving lead acetate 32 37 EN Mohammad Reza Khani Reza Bigdeli Hosssein Vazini Parmis Notghi Journal Article 2017 02 26 Background: Lead (Pb) is a one of the well-known dangerous contaminant Lead can cause disorders in the process of spermatogenesis. Using medicinal plants to cure impotence and lack of sex cells can have a positive effect. In this study, parsley extract on spermatogenesis in male rats which have received lead acetate is investigated. Methods: In the present study, 36 rats were divided into 6 groups of 6. Animals received lead acetate and extract of parsley for a period of 28 days. After 28 days, animals were weighted and were anesthetized by ether, then the body and testis were weighted and numbers of spermatocytes, spermatogonia, Leydig cells were studied. The obtained results were analyzed by ANOVA and Tukey tests. Results: Lead acetate significantly decreased the spermatocytes, spermatogonia, Leydig cells. Parsley extract with 200 mg/kg dose could lead to a significant increase of sperms in the tube lumen (p<0.05). Conclusion: Parsley’s extract effect on spermatogenesis in male rats which received lead acetate was justified.