Tabriz University of Medical Sciences Medical Journal of Tabriz University of Medical Sciences 2783-2031 41 1 2019 04 10 The effect of eight -week aerobic exercise and consumption of curcumin on TNF-α and medium-term memory in 60-65 years old women with syndrome metabolic 14 20 10.34172/mj.2019.002 EN Ali Osali https://orcid.org/0000-0002-9646-4605 Journal Article 10.34172/mj.2019.002 2016 12 31 Background: The aim of this research was to investigate the effect of eight-week aerobic exercise with moderate intensity and consumption of curcumin on TNF-α and Medium-term memory in 60-65 years old women with syndrome metabolic. Methods: 44 women with metabolic syndrome (MetS) voluntarily took part in the present study. Participants were randomly divided in 4 groups of MetS exercise+ Curcumin (MECU), MetS exercise (ME), MetS Curcumin (MCU), MetS control (MC). During the first week MECU group and ME participated in three sets of ten-minute aerobic exercise training with treadmill (AT) also they have 5 minute rest part between the sets. One minute was added to the duration of exercise sets weekly basis. Blood samples and memory test were conducted before and after eight -week. TNF-α level was measured by ELISA method and memory test were conduct with Picture recall test. To analyze the data, researcher made use of One-Way ANOVA, paired-sample t-test with the significance level of (P≤0.05). Results: After eight -week interventions TNF-α significantly decreased (P≤0.05). Also Medium-term memory significantly increased (P≤0.05). Conclusion: These findings indicate eight –week interventions induce to increase Medium-term memory and maybe this increasing relative to decreasing in TNF-α level and ameliorate in metabolic syndromes factors.