Tabriz University of Medical Sciences Medical Journal of Tabriz University of Medical Sciences 2783-2031 43 2 2021 06 03 Evaluation of maternal factors for the development of retinopathy of prematurity 173 178 10.34172/mj.2021.042 EN Amir Eftekhari https://orcid.org/0000-0002-1669-2497 Vahideh Manouchehri https://orcid.org/0000-0002-1214-7865 Farideh Mosavi https://orcid.org/0000-0002-0388-7749 Mohammad Ali Jahanbani https://orcid.org/0000-0003-4259-8031 Journal Article 10.34172/mj.2021.042 2019 08 11 Background: Since Retinopathy of prematurity (ROP) is a leading cause of childhood blindness, the identification of contributed risk factors is crucial. In recent years, great attention has been paid to maternal factors. The reason is that maternal factors can directly affect fetus via intrauterine hypoxia. However, the results of this studies are conflicting. The purpose of this study was to evaluate the effect of maternal factors on the development of ROP. Methods: In a prospective study, 150 premature infants with the gestational age of less than 32 weeks and birth weight of less than 1500 grams were examined. They divided into two groups based on ophthalmologic examination; those with ROP and those without ROP. Variables of study including maternal age, injection of corticosteroid in the last week of pregnancy, history of maternal diabetes mellitus, preeclampsia, hypertension, anemia, thyroid, renal, cardiovascular and rheumatologic diseases were compared between groups. Results: Forty-seven infants (31.33 %) had ROP. The mean age of gestational age was 27.89 weeks in ROP group and 29.06 weeks in non-ROP group. The mean birth weight was 1180.53 grams in ROP group and 1079.44 grams in non-ROP group. There were no statistically important differences regarding to maternal factors between two groups. Conclusion: The above mentioned maternal factors have no effect on the development of ROP.