Tabriz University of Medical Sciences Medical Journal of Tabriz University of Medical Sciences 2783-2031 42 6 2021 02 24 Reaction to surgicel in neurosurgery 781 786 10.34172/mj.2021.020 EN Mohammad Reza Ehsaei https://orcid.org/0000-0002-1562-1884 Mostafa Sadeghi https://orcid.org/0000-0001-6816-5571 Sara Rahimi https://orcid.org/0000-0003-4834-047X Behzad Gholamveisi https://orcid.org/0000-0002-8826-884X Journal Article 10.34172/mj.2021.020 2019 11 24 The use of Surgicel is one of the methods used to stop bleeding during various surgical operations, especially neurosurgery. The use of Surgicel may cause complications such as inflammation, delayed tissue repair, and necrosis. This case is a 60-year-old woman with a history of craniotomy and reaction to Surgicel who presented to the hospital with symptoms of seizures. The patient underwent craniotomy after a mass diagnosis in the parasagittal region. After reviewing this case, we concluded that the use of Surgicel can have complications for patients, Therefore, it is recommended to use Surgicel in the patient's body so that it is not treated as a mass, abscess, or hematoma in the postoperative period.