Tabriz University of Medical Sciences Medical Journal of Tabriz University of Medical Sciences 2783-2031 30 3 2008 09 22 Case Report of Focal Epithelial Hyperplasia in Tabriz 137 140 EN VOSOUGHHOSSEINI S YAZDANI J MORAD ZADEH M LOTFI M AGHBALI AA Journal Article 2009 11 21 Focal epithelial hyperplasia ( Heck disease) is a rare benign and contagious lesion that first time was reported in children of Eskimos and American Indian. Up to now only one case report of this lesion has been reported from Iran. High incidence of this lesion among family members indicates infectious pathogenesis. Human papilloma virus (subtype 13 and 32) has known as cause of this lesion. FEH usually characterizes by multiple soft nodules and papules in the oral mucosa specially on lips, buccal mucosa and the lateral border of the tongue. This article reports the first case of FEH in Tabriz and the second one in Iran.