Tabriz University of Medical Sciences Medical Journal of Tabriz University of Medical Sciences 2783-2031 29 3 2007 09 22 Cd 25/26(+T), Rare Mutation in β-Globin Gene 139 142 EN HOSSEINPOUR FEIZI AA HOSSEINPOUR FEIZI MA POULADI N HAGHI M AZARFAM P Journal Article 2010 05 05 β-thalassemia is a heterogenous group of genetic alteration characterized by a deficient synthesis (β+) or an absent (β°) of β- globin chains. However, between these two clinical forms there are a wide range of clinical phenotypes. We reported a very rare β° thalassmia mutation, Cd25/26(+T), in a family with normal body structure and transfusion dependent from Azerbaijan-Iran for the first time. The comparison of hemoglobin level revealed that they have a high level HbF (98%) that help their normal growth.