Tabriz University of Medical Sciences Medical Journal of Tabriz University of Medical Sciences 2783-2031 26 3 2004 10 22 A Case of Central Sleep Apnea and "Ondine Curse" due to Type 1 Chiari Malformation 108 111 EN khandaghi R HEJAZI MS FARZAN NIA A ARAMI MA Journal Article 2013 07 28 Sleep apnea is defined as an intermittent cessation of airflow at the nose and mouth during sleep.Sleep apneas have been classified into three types:central, obstructive, and mixed.In obstructive sleep apnea (OSA) airflow ceases despite continuing respiratory drive because of occlusion of the oropharyngeal airway.In contrast, in central sleep apnea (CSA) the neural drive to all the respiratory muscles is transiently abolished. Ondine curse is a loss of automatic or involuntary respiration during sleep. Sleep apnea and Ondine curse are rare presentations of type 1 Chiari malformation, and almost all reported cases were due to type 2 of malformation.Here we report a case of sleep apnea and Ondine curse in a patient with Chiari malformation type 1.