Tabriz University of Medical Sciences Medical Journal of Tabriz University of Medical Sciences 2783-2031 35 2 2013 06 05 Effect of Aerobic Exercise on Circadian Rhythm of MDA and PC in Healthy and Active Male Students 98 105 EN Javad Vakili Abbas Ali Gaeini Mehdi Hedayati Saeid Nikookheslat Maryam Akbari Vahid Tarmahi Journal Article 2012 09 02 2012 11 18 Backgrounds and Objectives: A few researches have performed about the circadian rhythm of oxidants. The aim of this study was to investigate effect of aerobic exhaustive exercise on Circadian rhythm of MDA and PC in a group of healthy active collegiate men with normal night sleep. Materials and Methods: In this study. For this reason, 10 active students with mean of age: 23/2±2/57 year's old, height: 174/5±6/35 cm and weight: 65/9±4/5 kg, voluntarily participated in this study. All participants followed recommended sleep- wake programs and diet regime during two weeks for synchronization. Their wake-sleep and diet programs were under supervision from the night of beginning of sampling up to 48 hours. Control and experimental, with one week interval between them. In control group, six blood samples were collected at 4 hourly intervals started 12:00 (mid-day) until the upcoming morning samples were collected from antecubital vein. In experimental group, similar protocol was implemented. Colorimetric chemical method was used for measuring MDA and PC factors. Repeated Measures ANOVA was used for statistical study. Results: The results showed that the plasma MDA levels exhibited a highly significant circadian rhythm in control (P = 0/014) and experimental (p=0/008) groups. But, There weren’t a significant circadian rhythm for PC factor (P<0/05). Conclusion: The result of this study showed that there is a high risk of oxidative stress injuries in the morning and exercise can vary affect rhythm of oxidative stress.