Tabriz University of Medical Sciences Medical Journal of Tabriz University of Medical Sciences 2783-2031 36 6 2015 02 05 Effect of Coenzyme Q10 Supplementation on Exercise Response in Some Hematological Parameters in Non-Athletes Men 28 33 EN Alireza Rostami Afshar Jafari Reza Mahmoodi Asghar Mahmoodi Journal Article 2013 11 20 2014 01 08 Background and Objectives: There is limited available data about the effects of antioxidant supplements on changes of hematological parameters after exercise. This study was carried out to investigate the effect of short-term CoenzymeQ10 supplementation on white blood cells, hemoglobin and red blood cell indices in non-athlete men after relatively intense running. Materials and Methods: Twenty healthy inactive men (25±3 years, fat 13±2. % and VO2max 41±2 ml/kg/min) in a randomized and double-blind design were allocated in two equal groups: supplement (2.5 mg/kg/day Coenzyme Q10) and placebo (2.5 mg/kg/day dextrose) groups. After the 14-day supplementation therapy, all subjects were participated in an aerobic exercise with 75% VO2max on the treadmill for 30 minutes. Blood samples obtained before the Q10 supplementation along with before and after the exercise protocol. Results: Ingestion 14-day coenzymQ10 supplementation on indexs (RBC, Hg, MCV, MCH, MCHC, Hct, WBC,PLT, lanphosit percentages, notrophils and other blood cells) had no significant effect (P>0.05) on basal parameters. Moreover, aerobic exercise causes lower red blood cells counts, hemoglobin and hematocrit and increase White blood cells and platelete (P<0.05), However, the rang of lower red blood cells, hemoglobin, hematocrit and increase white blood cells in supplementation group after aerobic exercise low was that placebo group (P<0.05). Conclusion: Tngestion 14-day coenzymQ10 supplementation (with 2/5 g/kg/day) in effective on withe blood cells, hemoglobin and red blood cell indices after that aerobic exercise.