Tabriz University of Medical Sciences Medical Journal of Tabriz University of Medical Sciences 2783-2031 45 1 2023 04 17 Evaluation of antibiotic resistance of Staphylococcus aureus and Pseudomonas aeruginosa strains isolated from blood samples in Qom Hazrat Masoumeh Children's Hospital during ten years 88 94 10.34172/mj.2023.016 EN Zahra Movahedi https://orcid.org/0000-0002-5847-6111 Alireza Sharifi Saeedeh Keshtkaran Maryam Sharifi Mehdi Zarei Mojde Bagheri Pooya Jafari Parisa Arab Maghsoudi https://orcid.org/0000-0002-5628-989X Journal Article 10.34172/mj.2023.016 2022 07 22 2022 10 03 Background. Antibiotic resistance is a phenomenon that occurs in different areas of the world against pathogens that cause nosocomial infections. This study aimed to evaluate the antibiotic resistance of Staphylococcus aureus and Pseudomonas aeruginosa strains. Methods. In this study, 340 patients with positive blood cultures by these two bacteria were reviewed. The data were analyzed using SPSS software. Results. For Staphylococcus aureus, the highest antibiotic resistance and sensitivity rates were 27/2 percent (25 cases) to vancomycin and 30/4 percent (28 cases) to gentamicin. In contrast, the resistance and sensitivity rates for pseudomonas aeruginosa were 11/7 percent (19 cases) to meropenem and 29/6 percent (48 cases) to gentamycin, respectively. Conclusion. Accurate evaluation of the antibiotic resistance pattern of these bacteria is necessary to select an effective antibiotic for the treatment of children. Practical Implications. We can provide beneficial and effective treatment using effective antibiotics on bacteria.